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KMID : 0614620100560010045
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Korean Journal of Gastroenterology
2010 Volume.56 No. 1 p.45 ~ p.48
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A Case of Hemophagocytic Syndrome in an Ulcerative Colitis
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Kim Yong-Chul
Kim Gun-Min
Lee Ho-Sang
Hong Seok-In
Cheung Dae-Young
Kim Jin-Il
Park Soo-Heon
Kim Jae-Kwang
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Abstract
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A case of hemophagocytic syndrome associated with ulcerative colitis is very rare. A 32-year-old man visited the hospital complaining of fever and severe abdominal pain for 7 days. He was diagnosed to have ulcerative colitis 2 years ago and had been treated with sulfasalazine. Three months ago, he had abdominal pain, weight loss, and hematochezia, so prednisolone and mercaptopurine were added to the treatment. On admission, the physical examination showed splenomegaly. Peripheral blood counts revealed pancytopenia, and bone marrow aspirate smears showed many histiocytes with active hemophagocytosis. There was no evidence of viral and bacterial infections and other neoplasms, which were commonly associated with hemophagocytic syndrome. He was successfully treated with high dose steroid. We report this case along with a review of the related literatures.
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KEYWORD
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Ulcerative colitis, Hemophagocytic syndrome
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